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Special Issue: The Immune System in Development and Regeneration

HUMAN DEVELOPMENT

Summary: This study provides versatile tools for the isolation, phenotyping and expansion of human fetal skin T cells, enabling the study of their complexity and heterogeneity allowing new research in skin development and immunity.

STEM CELLS AND REGENERATION

Summary: Toll2-2, one of 11 Toll-related receptors expressed in insect macrophages, induces cytokine expression and promotes cell proliferation during Gryllus bimaculatus leg regeneration.

Summary: This study is the first to show that resolving neutrophilic inflammation using a clinically approved immunomodulatory drug (AT7519) improves heart regeneration in zebrafish.

RESEARCH REPORT

Summary: Jak/Stat pathway activity mediates crosstalk between macrophages/microglia and retinal ganglion cells to regulate retinal ganglion cell survival after injury in zebrafish.

RESEARCH ARTICLES

Summary: The expression of MyD88 and IL10 in B cells is essential for appropriate in utero development and protects against LPS-induced preterm birth.

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