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Special Issue: Imaging Development, Stem Cells and Regeneration

PRIMER

Summary: This Primer explains and provides advice on two- and three-dimensional stress inference, an increasingly popular technique to identify the role of mechanics during embryo development.

RESEARCH ARTICLES

Summary: Use of the SunTag method to allow single-molecule imaging in fixed and live Drosophila embryos reveals translational repression of zygotic hunchback mRNAs.

Summary: Oriented cell movement at the leading edge mesendoderm surface allows this tissue to move by being pulled forward by cells at its front end.

TECHNIQUES AND RESOURCES

Summary: Introducing an easy-to-use automated anatomical phenotyping pipeline for mouse embryos along with a highly-detailed anatomical E14.5 atlas.

Summary: This paper presents a new computational pipeline for comparing and mapping global and local anatomical shape differences that is higher-resolution and requires less expertise and labour than traditional landmarking methods.

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