Skip Nav Destination

Issues

Select decade

Select year

Issue

Volume 140, Issue 1

January 2013

Previous issue
Next issue

All issues

Cover image

Cover Image

Cover: Immunofluorescent staining for amylase (purple) and E-cadherin (light blue) on a cryosection of E16.5 mouse pancreas. Modified in Photoshop v4 using the Glow Edge stylize filter. See Research article by Petzold et al. on p. 126.
Table of contents

ISSN 0950-1991

EISSN 1477-9129

In this issue

EDITORIAL
PRIMER
REVIEW
DEVELOPMENT AND STEM CELLS
RESEARCH REPORT
RESEARCH ARTICLE
TECHNIQUES AND RESOURCES
ERRATUM
IN THIS ISSUE
ARTICLE OF INTEREST IN OTHER COB JOURNALS
- FROM JOURNAL OF CELL SCIENCE

EDITORIAL

Reprogramming development

Olivier Pourquié

Extract

View articletitled, Reprogramming development

Open the PDF for in another window

PRIMER

Primer Series

Endoreplication and polyploidy: insights into development and disease

Donald T. Fox,Robert J. Duronio

Abstract

View articletitled, Endoreplication and polyploidy: insights into development and disease

Open the PDF for in another window

REVIEW

Cell polarity: models and mechanisms from yeast, worms and flies

Barry J. Thompson

Abstract

View articletitled, Cell polarity: models and mechanisms from yeast, worms and flies

Open the PDF for in another window

DEVELOPMENT AND STEM CELLS

MicroRNAs downregulate Bag of marbles to ensure proper terminal differentiation in the Drosophila male germline

Suk Ho Eun,Patrick M. Stoiber,Heather J. Wright,Karen E. McMurdie,Caitlin H. Choi,Qiang Gan,Cindy Lim,Xin Chen

Abstract

View articletitled, MicroRNAs downregulate Bag of marbles to ensure proper terminal differentiation in the Drosophila male germline

Supplementary information

Open the PDF for in another window

MEF2A regulates the Gtl2-Dio3 microRNA mega-cluster to modulate WNT signaling in skeletal muscle regeneration

Christine M. Snyder,Amanda L. Rice,Nelsa L. Estrella,Aaron Held,Susan C. Kandarian,Francisco J. Naya

Abstract

View articletitled, MEF2A regulates the Gtl2-Dio3 microRNA mega-cluster to modulate WNT signaling in skeletal muscle regeneration

Supplementary information

Open the PDF for in another window

Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition

Dario Acampora,Luca G. Di Giovannantonio,Antonio Simeone

Abstract

View articletitled, Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition

Supplementary information

Open the PDF for in another window

Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis

Marc Amoyel,Justina Sanny,Michael Burel,Erika A. Bach

Abstract

View articletitled, Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis

Supplementary information

Open the PDF for in another window

Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium

Akihiro Hirata,Jochen Utikal,Satoshi Yamashita,Hitomi Aoki,Akira Watanabe,Takuya Yamamoto,Hideyuki Okano,Nabeel Bardeesy,Takahiro Kunisada,Toshikazu Ushijima,Akira Hara,Rudolf Jaenisch,Konrad Hochedlinger,Yasuhiro Yamada

Abstract

View articletitled, Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium

Supplementary information

Open the PDF for in another window

RESEARCH REPORT

Distinct requirements for wnt9a and irf6 in extension and integration mechanisms during zebrafish palate morphogenesis

Max Dougherty,George Kamel,Michael Grimaldi,Lisa Gfrerer,Valeriy Shubinets,Renee Ethier,Graham Hickey,Robert A. Cornell,Eric C. Liao

Abstract

View articletitled, Distinct requirements for wnt9a and irf6 in extension and integration mechanisms during zebrafish palate morphogenesis

Supplementary information

Open the PDF for in another window

RESEARCH ARTICLE

A Hh-driven gene network controls specification, pattern and size of the Drosophila simple eyes

Daniel Aguilar-Hidalgo,María A. Domínguez-Cejudo,Gabriele Amore,Anette Brockmann,María C. Lemos,Antonio Córdoba,Fernando Casares

Abstract

View articletitled, A Hh-driven gene network controls specification, pattern and size of the Drosophila simple eyes

Supplementary information

Open the PDF for in another window

Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism

Jörn Schweitzer,Heiko Löhr,Joshua L. Bonkowsky,Katrin Hübscher,Wolfgang Driever

Abstract

View articletitled, Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism

Supplementary information

Open the PDF for in another window

The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi

Andrei Avanesov,Seth S. Blair

Abstract

View articletitled, The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi

Supplementary information

Open the PDF for in another window

Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation

Emanuela S. Milani,Heike Brinkhaus,Regula Dueggeli,Ina Klebba,Urs Mueller,Michael Stadler,Hubertus Kohler,Matthew J. Smalley,Mohamed Bentires-Alj

Abstract

View articletitled, Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation

Supplementary information

Open the PDF for in another window

Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas

Kristin M. Petzold,Heike Naumann,Francesca M. Spagnoli

Abstract

View articletitled, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas

Supplementary information

Open the PDF for in another window

Genetic elevation of Sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila

Mario Pantoja,Karin A. Fischer,Nicholas Ieronimakis,Morayma Reyes,Hannele Ruohola-Baker

Abstract

View articletitled, Genetic elevation of Sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila

Supplementary information

Open the PDF for in another window

A transiently expressed connexin is essential for anterior neural plate development in Ciona intestinalis

Christopher Hackley,Erin Mulholland,Gil Jung Kim,Erin Newman-Smith,William C. Smith

Abstract

View articletitled, A transiently expressed connexin is essential for anterior neural plate development in Ciona intestinalis

Supplementary information

Open the PDF for in another window

The catalytic subunit of Arabidopsis DNA polymerase α ensures stable maintenance of histone modification

Youbong Hyun,Hyein Yun,Kyunghyuk Park,Hyonhwa Ohr,Okchan Lee,Dong-Hwan Kim,Sibum Sung,Yeonhee Choi

Abstract

View articletitled, The catalytic subunit of Arabidopsis DNA polymerase α ensures stable maintenance of histone modification

Supplementary information

Open the PDF for in another window

Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition

Cédric Hesling,Jonathan Lopez,Laurent Fattet,Philippe Gonzalo,Isabelle Treilleux,Daphné Blanchard,Régine Losson,Vincent Goffin,Natascha Pigat,Alain Puisieux,Ivan Mikaelian,Germain Gillet,Ruth Rimokh

Abstract

View articletitled, Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition

Supplementary information

Open the PDF for in another window

The Abelson tyrosine kinase regulates Notch endocytosis and signaling to maintain neuronal cell fate in Drosophila photoreceptors

Wenjun Xiong,Santiago A. Morillo,Ilaria Rebay

Abstract

View articletitled, The Abelson tyrosine kinase regulates Notch endocytosis and signaling to maintain neuronal cell fate in Drosophila photoreceptors

Supplementary information

Open the PDF for in another window

Auxin controls petal initiation in Arabidopsis

Edwin R. Lampugnani,Aydin Kilinc,David R. Smyth

Abstract

View articletitled, Auxin controls petal initiation in Arabidopsis

Supplementary information

Open the PDF for in another window

JAK/STAT autocontrol of ligand-producing cell number through apoptosis

Antoine Borensztejn,Elisabeth Boissoneau,Guillaume Fernandez,François Agnès,Anne-Marie Pret

Abstract

View articletitled, JAK/STAT autocontrol of ligand-producing cell number through apoptosis

Supplementary information

Open the PDF for in another window

Competition among gene regulatory networks imposes order within the eye-antennal disc of Drosophila

Bonnie M. Weasner,Justin P. Kumar

Abstract

View articletitled, Competition among gene regulatory networks imposes order within the eye-antennal disc of Drosophila

Supplementary information

Open the PDF for in another window

TECHNIQUES AND RESOURCES

A continuum of transcriptional identities visualized by combinatorial fluorescent in situ hybridization

Lars Martin Jakt,Satoko Moriwaki,Shinichi Nishikawa

Abstract

View articletitled, A continuum of transcriptional identities visualized by combinatorial fluorescent in situ hybridization

Supplementary information

Open the PDF for in another window

In toto live imaging of mouse morphogenesis and new insights into neural tube closure

R’ada Massarwa,Lee Niswander

Abstract

View articletitled, In toto live imaging of mouse morphogenesis and new insights into neural tube closure

Supplementary information

Open the PDF for in another window

Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter

Takaya Abe,Asako Sakaue-Sawano,Hiroshi Kiyonari,Go Shioi,Ken-ichi Inoue,Toshitaka Horiuchi,Kazuki Nakao,Atsushi Miyawaki,Shinichi Aizawa,Toshihiko Fujimori

Abstract

View articletitled, Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter

Supplementary information

Open the PDF for in another window

ERRATUM

A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea

Bonnie E. Jacques,Chandrakala Puligilla,Rachel M. Weichert,Anna Ferrer-Vaquer,Anna-Katerina Hadjantonakis,Matthew W. Kelley,Alain Dabdoub

Extract

View articletitled, A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea

Open the PDF for in another window

HIF1α is a central regulator of collagen hydroxylation and secretion under hypoxia during bone development

Lital Bentovim,Roy Amarilio,Elazar Zelzer

Extract

View articletitled, HIF1α is a central regulator of collagen hydroxylation and secretion under hypoxia during bone development

Open the PDF for in another window

IN THIS ISSUE

ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM JOURNAL OF CELL SCIENCE

Schwann cell myelination requires integration of laminin activities

K. K. McKee,D.-H. Yang,R. Patel,Z.-L. Chen,S. Strickland,J. Takagi,K. Sekiguchi,P. D. Yurchenco

View articletitled, Schwann cell myelination requires integration of laminin activities

The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes

B. J. Loh,C. F. Cullen,N. Vogt,H. Ohkura

View articletitled, The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes

Email alerts

Accepted manuscripts alert

Table of contents alert

Latest published articles alert

Accepted manuscripts

A chromatin remodelling SWI/SNF subunit Snr1 regulates neural stem cell determination and differentiation

Sophie E. Keegan, Julie Haskins, Andrew J. Simmonds, Sarah C. Hughes

DNA methylation dynamic in male rat germ cells during gametogenesis

Rhizlane El Omri-Charai, Isabelle Gilbert, Julien Prunier, Rebecka Desmarais, Mariana Gabriela Ghinet, Claude Robert, Guylain Boissonneault, Géraldine Delbes

DeXtrusion: Automatic recognition of epithelial cell extrusion through machine learning in vivo

Alexis Villars, Gaëlle Letort, Léo Valon, Romain Levayer

Molecular mechanism of synovial joint site specification and induction in developing vertebrate limbs

Upendra S. Yadav, Tathagata Biswas, Pratik N. Singh, Pankaj Gupta, Soura Chakraborty, Irene Delgado, Hamim Zafar, Terence D. Capellini, Miguel Torres, Amitabha Bandyopadhyay

Tools to analyze the organization and formation of the germline cyst in zebrafish oogenesis

Vineet Kumar, Yaniv Elkouby

More accepted manuscripts

RSS Feeds

RSS Feed - Current Issue Only

Open Issues RSS Feed

The Forest of Biologists is a biodiversity initiative created by The Company of Biologists, with support from the Woodland Trust. For every Research and Review article published in Development a native tree is planted in a UK forest. In addition to this we are protecting and restoring ancient woodland and are dedicating these trees to our peer reviewers. Visit our virtual forest to learn more.

Propose a new Workshop for 2025

We are now accepting proposals for our 2025 Biologists Workshops programme. As the scientific organiser, your involvement will be focused on the science. We'll take care of all the logistics. In 2025 we'll continue our efforts to diversify our Workshop programme and will be reserving one of our Workshops for an application from a Global South (GS) country to host an event overseas.

Development presents… Outstanding Paper Prize Finalists

On Wednesday 19 April, Development hosted a webinar celebrating the finalists for Development’s Inaugural Outstanding Paper Prize. The talks and Q&As were hosted by our Deputy Editor, Steve Wilson (UCL).

Development Journal Meeting 2023

Advertisement banner depicting a Fluorescently tagged organism

The Abstract deadline for our 2023 Journal Meeting ‘Unconventional and Emerging Experimental Organisms in Cell and Developmental Biology’ is 23 June 2023. Find out more and apply to Developments 2023 Journal Meeting here.

Keeping up with the Node

Thirteen years on from its launch, the Node continues to be a place to share research stories, opinions, job adverts and event listings. Development have published a recent Editorial showcasing some of our most popular features, as well as introducing some new initiatives.

Issues

Cover Image

EDITORIAL

PRIMER

REVIEW

DEVELOPMENT AND STEM CELLS

RESEARCH REPORT

RESEARCH ARTICLE

TECHNIQUES AND RESOURCES

ERRATUM

IN THIS ISSUE

ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM JOURNAL OF CELL SCIENCE

Email alerts

RSS Feeds

This Feature Is Available To Subscribers Only