Issues
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Cover image
Cover Image
Cover: Confocal section of an Oct4 mutant mouse embryo around the time of implantation, showing localisation of the transcription factor Cdx2 (red; yellow in merge) in nuclei (green) of inside and outside cells of the embryo. Oct4 represses Cdx2 in epiblast cells at implantation, but not at earlier stages. See Research article by Ralston et al. on p. 359. - PDF Icon PDF LinkTable of contents
SPOTLIGHT
REVIEW
DEVELOPMENT AND STEM CELLS
RESEARCH ARTICLE
Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer
ARTICLE OF INTEREST IN OTHER COB JOURNALS
FROM JOURNAL OF CELL SCIENCE
IN THIS ISSUE
History of our journals

As our publisher, The Company of Biologists, turns 100 years old, read about Development’s journey and highlights from some its first issues, and explore the history of each of our sister journals: Journal of Cell Science, Journal of Experimental Biology, Disease Models & Mechanisms and Biology Open.
Call for papers – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues

Development invites you to submit your latest research to our upcoming special issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues. This issue will be coordinated by Guest Editors Meritxell Huch (Max Planck Institute of Molecular Cell Biology and Genetics, Germany) and Mansi Srivastava (Harvard University and Museum of Comparative Zoology, USA), working alongside our team of academic Editors. Submit your articles by 15 May 2025.
A case for broadening our view of mechanism in developmental biology

In this Perspective, B. Duygu Özpolat and colleagues survey researchers on their views on what it takes to infer mechanism in developmental biology. They examine what factors shape our idea of what we mean by ‘mechanism’ and suggest a path forward that embraces a broad outlook on the diversity of studies that advance knowledge in our field.
In preprints
Did you know that Development publishes perspectives on recent preprints? These articles help our readers navigate the ever-growing preprint literature. We welcome proposals for ‘In preprints’ articles, so please do get in touch if you’d like to contribute.