Cover ImageCover: Cells in Xenopus embryos are full of yolk platelets. As the embryo develops, this intracellular food source is consumed. Individual embryonic cells contain yolk platelets that are being actively digested (white, labelled for major yolk protein) as well as yolk platelets that remain dormant (blue, labelled for the novel yolk protein Seryp). See Research article by Jorgensen et al. on p. 1539.
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RacGAP50C directs perinuclear γ-tubulin localization to organize the uniform microtubule array required for Drosophila myotube extension
Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation
C. elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV
Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects
Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11
The APC/C E3 ligase remains active in most post-mitotic Arabidopsis cells and is required for proper vasculature development and organization
Functional diversity of R3 single-repeat genes in trichome development
Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells
A gain-of-function mutation in IAA18 alters Arabidopsisembryonic apical patterning
Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants
The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus
Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei
Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2
DEVELOPMENT AND DISEASE
Drosophila Tubulin-specific chaperone E functions at neuromuscular synapses and is required for microtubule network formation
The sea urchin animal pole domain is a Six3-dependent neurogenic patterning center
ARTICLE OF INTEREST IN OTHER COB JOURNALS
FROM JOURNAL OF CELL SCIENCE
NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development
PP2A regulates BMP signalling by interacting with BMP receptor complexes and by dephosphorylating both the C-terminus and the linker region of Smad1
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