Cover ImageCover: Neonatal mouse cerebellum sagittal section immunostained for the glial marker GFAP (green) and insulin receptor substrate 1 (IRS1, red). IRS1 is found in proliferating cerebellar neural precursors, located in the external granule layer, and it is excluded from glia. IRS1 is necessary for cerebellar granule neuron precursor expansion. See research article by Parathath et al. on p. 3291.
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Regulative feedback in pattern formation: towards a general relativistic theory of positional information
GATA transcription factors integrate Wnt signalling during heart development
A dual requirement for Iroquois genes during Xenopus kidney development
Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis
Polycomb-dependent Ultrabithorax Hox gene silencing induced by high Ultrabithorax levels in Drosophila
Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption
Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis
Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development
In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis
A ryanodine receptor-dependent Cai2+ asymmetry at Hensen's node mediates avian lateral identity
Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum
DEVELOPMENT AND DISEASE
Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors
Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4
Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling
ARTICLE OF INTEREST IN OTHER COB JOURNALS
FROM JOURNAL OF CELL SCIENCE
Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development
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