2020 collection: Mechanics and Morphogenesis
Welcome to Development’s subject collection on Mechanics and Morphogenesis
Morphogenesis - the shaping of tissues and organs into their appropriate form during development - involves a complex repertoire of cellular behaviours that must be tightly controlled in space and time. These cellular behaviours both generate and react to mechanical forces that deform tissues as they develop. Moreover, feedback between mechanical and chemical inputs provides an important layer of regulation, often operating at the level of the cytoskeleton.
This subject collection highlights a selection of recent review and research papers that focus on the mechanics of morphogenesis across a range of animal species - from Drosophila to mouse. As well as showcasing recent conceptual advances in how physical forces are harnessed to control tissue shape, they also emphasize the diverse approaches - both experimental and computational - that are needed to understand the mechanics of morphogenesis.