The mitochondrial enzyme, succinate dehydrogenase, can be localized by specific histochemical stains. A naturally occurring variant which gives heat-labile enzyme is used to map a gene responsible for succinate dehydrogenase. New alleles at the sdh locus are produced by mutagenesis and most of these are found to be homozygous lethal to flies. However, clones of cells which are homozygous for the new alleles can be produced by mitotic recombination, and are found to develop normally. If the chromosome arm bearing an sdh allele also carried brown, clones can be found in the eye. At the border of the clone the brown and sdh phenotype coincide showing that the sdh phenotype is expressed as a cell autonomous marker. Clones of sdh have been observed in the adult epidermis, the muscles, the gut, the heart and oenocytes where they display a clear phenotype. This new marker may be useful in studying the development of the internal organs of Drosophila.
Development Journal Meeting 2022: From Stem Cells to Human Development
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Following a virtual meeting in 2020, we are delighted to announce that the fifth iteration of our popular Journal Meeting will be held from 11-14 September 2022 at the historic Wotton House, Surrey. Registration is open now.
Special Issue: The Immune System in Development and Regeneration
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Our latest special issue is now complete. It showcases articles that add to the repertoire of immune cell functions during development, repair and regeneration, and provide insights into the developmental pathways leading to the generation and dispersal of these cells. You can watch recordings from our Development presents... webinar celebrating the special issue here.
Propose a new Workshop
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Our Workshops bring together leading experts and early-career researchers from a range of scientific backgrounds. Applications are now open to propose Workshops for 2024, one of which will be held in a Global South country.
Preprints in Development
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As part of our efforts to support the use of preprints and help curate the preprint literature, we are delighted to launch a new article type: ‘In preprints’. These pieces will discuss one or more recent preprints and place them in a broader context. You can read the first article here.
FocalPlane Network launched
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Like the Node Network, the aim of the FocalPlane Network is to facilitate promotion and networking as well as assist those seeking conference speakers, committee members, reviewers or collaborators. We hope that it will help promote diversity in the community. Find out more and join the Network here.
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