A round-up of preLights posts related to preprints in developmental biology, posted between mid-January 2022 and early-May 2022
FGF signalling promotes precursor spreading for adult adipogenesis in Drosophila by Lei et al.
Out with the old, in with the new: during fly metamorphosism the adult fat body develops de novo with a hand from FGF signalling
Selected by Anastasia Moraiti, read the preLight here
Cell Rearrangement Generates Pattern Emergence as a Function of Temporal Morphogen Exposure by Fulton et al.
What does it take to study patterning in a tissue as it grows? “Live modelling” combines cell tracking, quantitative imaging, and mathematical modelling to give insight into how cell movements tune morphogen exposure
Selected by Andrew Montequin, read the preLight here
Synthetic memory circuits for programmable cell reconfiguration in plants by Lloyd et al. and Synthetic genetic circuits enable reprogramming of plant roots by Brophy et al.
Synthetic gene circuits – a promising way to create ideotypical plant architecture
Selected by Gwendolyn K. Kirschner, read the preLight here
Combinatorial interactions of Hox genes establish appendage diversity of the amphipod crustacean Parhyale hawaiensis by Alberstat et al. and Distinct regulation of Hox genes by Polycomb Group genes in a crustacean by Sun et al.
A double feature on crustacean Hox regulation
Selected by Olivia Tidswell, read the preLight here
A cell fate decision map reveals abundant direct neurogenesis in the human developing neocortex by Coquand et al.
In the spotlight: how human neural progenitors were caught red-handed
Selected by Juan Moriano, read the preLight here
Absolute scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells by Kim & Ramalho-Santos
Quantifying the absolute RNA content of single cells is possible for existing data sets and biologically relevant
Selected by Vanessa Luzak, read the preLight here
Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition by Gleason et al.
Cha-cha-cha…Histones coordinated dance during development
Selected by Chee Kiang Ewe, read the preLight here
Annelid functional genomics reveal the origins of bilaterian life cycles by Liang et al.
Could the timing of trunk formation be a major driver in larval evolution?
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality by Sabate-Soler et al.
Ever wondered how we can model the human brain in a dish? Organoids and assembloids mimic the structure and complexity of the human brain
Selected by Emma Wilson, read the preLight here
Microstructured hydrogels to guid self-assembly and function of lung alveolospheres by Loebel et al.
Hyaluronic acid-based hydrogels with microcavities can be used to generate uniform lung alveolospheres
Selected by Julio Sainz de Aja, read the preLight here
Species-specific mitochondria dynamics and metabolism regulate the timing of neuronal development by Iwata et al.
Metabolism regulates developmental timing