Self-organised symmetry breaking in zebrafish reveals feedback from morphogenesis to pattern formation by Trivedi et al.
Pescoids - a new in vitro model system to study early zebrafish embryogenesis.
Selected by Sundar Naganathan. Read the preLight here
The nuclear to cytoplasmic ratio directly regulates zygotic transcription in Drosophila by Wilky et al.
Switching it up: the nuclear-cytoplasmic ratio directly regulates transcription of a switch-like gene, while indirectly affecting other zygotic genes.
Selected by Jessica Xie. Read the preLight here
Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications by Touceda-Suárez et al.
On the origin of gene deserts: large intergenic regions in vertebrates likely originated from exon erosion.
Selected by Jesus Victorino. Read the preLight here
The enteric nervous system of the human and mouse colon at a single-cell resolution by Drokhlyansky et al.
Meet the 1%: single-cell RNAseq of human & mouse enteric nervous system reveals core transcriptional programs of enteric neurons, DEGs by circadian phase & colon location, new models for intestinal peristalsis, neuro-immune interactions, and more!
Selected by Jessica Xie. Read the preLight here
KMT5C displays robust retention and liquid-like behavior in phase separated heterochromatin by Strickfaden et al.
Another liquid state - heterochromatin protein KMT5C displays liquid behavior only within its functional context at the pericentromere.
Selected by Carmen Adriaens. Read the preLight here
Ephrin-B1 blocks adult cardiomyocyte proliferation and heart regeneration by Cauquil et al.
A new link between CM rod shape and proliferation - Ephrin B1 sequestration of Yap1 at the lateral membrane.
Selected by Suraj Kannan. Read the preLight here
GeneWalk identifies relevant gene functions for a biological context using network representation learning by Ietswaart et al.
Fear The Walking Gene: knowledge-based machine learning is able to highlight gene functions relevant for a distinct biological context.
Selected by Ramona Jühlen. Read the preLight here
Mammalian Y RNAs are modified at discrete guanosine residues with N-glycans by Flynn et al.
The Discovery of Glycosylated RNA.
Selected by Connor Rosen. Read the preLight here
Mitochondrial RNA granules are fluid condensates, positioned by membrane dynamics by Rey et al.
Understanding mitochondrial RNA granules with an arsenal of advanced microscopy techniques.
Selected by Romain Laine. Read the preLight here
Polypyrimidine Tract Binding Proteins are essential for B cell development by Monzón-Casanova et al.
B cell stutter: B cells fail to develop in PTBP1/2 double knock outs.
Selected by Jonny Coates. Read the preLight here
HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa by Tittelmeier et al.
Two sides of the same coin: Hsp110 activity protects against amorphous protein aggregation, but promotes amyloid aggregation and toxicity in C. elegans models.
Selected by Tessa Sinnige. Read the preLight here
COMET: A toolkit for composing customizable genetic programs in mammalian cells by Donahue et al.
Reaching for the shooting stars: a COMET toolkit for bespoke mammalian cell genetic programming.
Selected by Zhang-He Goh. Read the preLight here
