Three-dimensional tissue stiffness mapping in the mouse embryo supports durotaxis during early limb bud morphogenesis by Zhu et al.
A new way of measuring the mechanical properties of bulk tissues in vivo identifies a stiffness gradient in the developing limb that correlates with patterns of cell migration.
Selected by Natalie Dye. Read the preLight here.
Single-cell RNA sequencing reveals novel cell differentiation dynamics during human airway epithelium regeneration by Garcia et al.
By single cell RNA sequencing airway epithelial cells during their differentiation from basal progenitor cells to mature epithelial cell types, the authors of this preprint throw light on the step-wise differentiation of the respiratory epithelium.
Signaling dynamics control cell fate in the early Drosophila embryo by Johnson et al.
How can the same molecule specify different dev outcomes? By systematically inducing Erk signalling using optogenetics, a preprint by the Toettcher lab suggests that differences in the dynamics of signalling underlie different cell fates in fly embryos.
Selected by Yara Sanchez Corrales. Read the preLight here
Transcriptional initiation and mechanically driven self-propagation of a tissue contractile wave during axis elongation by Bailles et al.
A mechanical relay mechanism drives a wave of polarized constriction during Drosophila endoderm morphogenesis.
Selected by Sundar Naganathan. Read the preLight here
Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells by Hollerer et al.
Toggling promoters and open reading frames to regulate gene expression.
Selected by Clarice Hong. Read the preLight here
Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells by Xia et al.
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Superresolution architecture of pluripotency guarding adhesions by Stubb et al.
Stem cell focal adhesions are structurally different to those of differentiated cells and maintain pluripotency.
Selected by Nicola Stevenson and Amanda Haage. Read the preLight here
Actomyosin-driven tension at compartmental boundaries orients cell division independently of cell geometry in vivo by Scarpa et al.
The century old Hertwig's rule in doubt: is the long cell axis rule valid in tissues?
Selected by Ivana Viktorinova. Read the preLight here
A histidine kinase gene is required for large radius root tip circumnutation and surface exploration in rice by Lehner et al.
Exploring the unseen: a putative histidine kinase promotes helical growth and soil surface exploration of rice roots.
Selected by Martin Balcerowicz. Read the preLight here
Comparative analysis of droplet-based ultra-high-throughput single-cell RNA-seq systems by Zhang et al.
Dropping some knowledge: A systematic comparison of droplet-based single-cell RNA-seq techniques.
Selected by Samantha Seah. Read the preLight here
PlotsOfData - a web app for visualizing data together with its summaries by Postma and Goedhart
Plot all your data with PlotsOfData.
Selected by Guillaume Jacquemet. Read the preLight here