In Development 142, 2704-2718, the data presented in Figure 2F indicated that there was a significant reduction in acetylated microtubules in stage Ia and Ib dachsous1b oocytes compared with wild-type oocytes, but that dachsous1b and wild-type oocytes were comparable by stage II of oogenesis. Based on these data and other oocyte analyses reported in the paper, we concluded that dachsous1b oogenesis is largely unaffected. The second author (M.M.F.) admitted that, without the knowledge of the other authors, she manipulated the stage Ia and stage Ib mutant data shown in the original Figure 2F. Therefore, we repeated this experiment and examined five wild-type and five dachsous mutant ovaries (>20 oocytes per genotype per stage), and found no significant differences in acetylated microtubules between wild-type and dachsous mutant oocytes at any of the stages examined. These new data, which are presented in the corrected figure (below), further support the overall conclusion reported in the original paper that oogenesis is intact in dachsous1b mutants. As the major conclusions of the paper are not affected, the journal editors – following consultation with all authors and the Academic Affairs Committee at Albert Einstein College of Medicine – have agreed that a Correction should be provided, with an explanation of the circumstances. This course of action complies with the journal's policy on correction of issues in the scientific record, which states: ‘Should an error appear in a published article that affects scientific meaning or author credibility but does not affect the overall results and conclusions of the paper, our policy is to publish a Correction’. We regret any confusion this may have caused.
Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis
Nanbing Li-Villarreal, Meredyth M. Forbes, Andrew J. Loza, Jiakun Chen, Taylur Ma, Kathryn Helde, Cecilia B. Moens, Jimann Shin, Atsushi Sawada, Anna E. Hindes, Julien Dubrulle, Alexander F. Schier, Gregory D. Longmore, Florence L. Marlow, Lilianna Solnica-Krezel; Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development 15 May 2016; 143 (10): 1832. doi: https://doi.org/10.1242/dev.138859
Download citation file:
Advertisement
Cited by
Biologists @ 100 - join us in Liverpool in March 2025

We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate the Spring Meetings of the BSCB and the BSDB, the JEB Symposium Sensory Perception in a Changing World and a DMM programme on antimicrobial resistance. Find out more and register by 28 February 2025 to join us in March 2025 in Liverpool, UK.
Call for papers – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues

Development invites you to submit your latest research to our upcoming special issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues. This issue will be coordinated by Guest Editors Meritxell Huch (Max Planck Institute of Molecular Cell Biology and Genetics, Germany) and Mansi Srivastava (Harvard University and Museum of Comparative Zoology, USA), working alongside our team of academic Editors. Submit your articles by 15 May 2025.
A case for broadening our view of mechanism in developmental biology

In this Perspective, B. Duygu Özpolat and colleagues survey researchers on their views on what it takes to infer mechanism in developmental biology. They examine what factors shape our idea of what we mean by ‘mechanism’ and suggest a path forward that embraces a broad outlook on the diversity of studies that advance knowledge in our field.
In preprints
Did you know that Development publishes perspectives on recent preprints? These articles help our readers navigate the ever-growing preprint literature. We welcome proposals for ‘In preprints’ articles, so please do get in touch if you’d like to contribute.