The WUSCHEL (WUS) family of transcription factors is well known for its role in stem cell maintenance in seed plants. There are two paralogues of the WUS-RELATED HOMEOBOX 13 (WOX13) gene in the moss Physcomitrella patens, but their function is unknown. Now, on p. , Mitsuyasu Hasebe, Thomas Laux and colleagues investigate the role of the WUX13L paralogues in moss and find that the two genes act redundantly to promote stem cell formation, but via a mechanism that differs from that of seed plants. Using a double knockout of the WOX13L paralogues, the authors show that WOX13L activity is required to initiate the cell growth that is necessary for stem cell formation from detached leaves. Further transcriptome analysis of the double mutant compared with wild-type moss reveals that the WOX13L genes are required for the upregulation of cell wall-loosening genes, revealing a novel function of the WOX gene family.
Skip Nav Destination
-HUBSwebinar.jpg?versionId=4486)
(update)-InPreprints.png?versionId=4486)
Article navigation
April 2014
Pathway to Independence programme
We’re excited to announce our new Pathway to Independence programme, aimed at supporting postdocs as they go on the job market. Find out more about the scheme in our Editorial.
Call for papers: Metabolic and Nutritional Control of Development and Regeneration
We are welcoming submissions for our next special issue, which will focus on metabolic and nutritional control of development and regeneration. Submission deadline: 15 May 2023.
Webinar: Increasing the visibility and impact of your research
Would you like to increase the visibility and impact of your research and raise your profile internationally? If so, register for the very practical webinar we are running in association with HUBS on 23 February 2023.
Transitions in development: Daniel Grimes
Daniel Grimes’s lab studies the consequences of ciliary mutations, including left-right patterning defects and scoliosis. We interviewed Daniel to find out more about his career path, his experience of becoming a group leader and the influence of Jurassic Park.
Preprints in Development
As part of our efforts to support the use of preprints and help curate the preprint literature, we are delighted to launch a new article type: ‘In preprints’. These pieces will discuss one or more recent preprints and place them in a broader context.
Social media
