Despite recent successes with the cultivation of mouse and rabbit eggs (references in Austin, 1961, pp. 144–7) techniques for the cultivation of post-implantation mammalian embryos have not hitherto advanced beyond those devised in the 1930's. Jolly & Lieure (1938) obtained development of rat and guinea-pig embryos explanted into homologous serum at stages between primitive streak and a few somites. They report that of their explanted rat embryos 37 per cent, developed an embryonic axis with a rhythmically beating heart, but only 9 per cent, a functioning circulation. None formed limb buds or a functioning allantoic circulation. Nicholas & Rudnick (1934, 1938) appear to have had a similar degree of success with rat embryos explanted into heparinized rat plasma and embryo extract. Waddington & Waterman (1933) explanted rabbit blastodiscs of primitive streak to 3-somite stages on to plasma clots; in the most successful cultures a 6–9 somite embryo was obtained with neural tube and beating heart, but without any blood circulation.
Development Journal Meeting 2022: From Stem Cells to Human Development
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Following a virtual meeting in 2020, we are delighted to announce that the fifth iteration of our popular Journal Meeting will be held from 11-14 September 2022 at the historic Wotton House, Surrey. Registration is open now.
Special Issue: The Immune System in Development and Regeneration
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Our latest special issue is now complete. It showcases articles that add to the repertoire of immune cell functions during development, repair and regeneration, and provide insights into the developmental pathways leading to the generation and dispersal of these cells.
Propose a new Workshop
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Our Workshops bring together leading experts and early-career researchers from a range of scientific backgrounds. Applications are now open to propose Workshops for 2024, one of which will be held in a Global South country.
Preprints in Development
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As part of our efforts to support the use of preprints and help curate the preprint literature, we are delighted to launch a new article type: ‘In preprints’. These pieces will discuss one or more recent preprints and place them in a broader context. You can read the first article here.
FocalPlane Network launched
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Like the Node Network, the aim of the FocalPlane Network is to facilitate promotion and networking as well as assist those seeking conference speakers, committee members, reviewers or collaborators. We hope that it will help promote diversity in the community. Find out more and join the Network here.
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