ABSTRACT
Using microdensitometry techniques the points in the cycle where blastemal cells become blocked after X-irradiation or denervation of the regenerating amphibian limb have been identified. X-irradiation blocks the cells in both G1 and G2 and those cells that were in S at the time of irradiation presumably proceed to G2. After denervation, however, cells accumulate only in Gx and those that were in S or G2 continue through the cycle to the next Gx. The latter results are clearly contradictory to a recent theory proposing a G2 neurotrophic control of blastemal cells and a solution to the contradiction is presented in the light of recent results.
Copyright © 1979 by Company of Biologists
1979
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