ABSTRACT
Neurulation and interkinetic nuclear migration in the chick embryo
Neurulation and interkinetic nuclear migration were studied in cells of the forming neural tube of chick embryos submitted to a variety of treatments. Our results show that cytochalasin B (5 μg/ml) does not protect microtubules against disruption occurring after 3h at 2 °C nor does it prevent their repolymerization once they are cold-disrupted. However, db-cAMP protects microtubules against such cold disruption. We indicate that the inhibitory effect of cytochalasin B on interkinetic nuclear migration cannot be ascribed to an effect on microtubules.
copyright © 1975 by Company of Biologists
1975
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