The behaviour of rat mast cells under conditions of high and low vitamin A

The authors have studied the mast cells in normal rats and in rats under hypo- and hyper-vitaminosis A. The main results of their studies are: (a) in the skin (dermis), in the case of A hypervitaminosis, there is a significant rise in the number of the mastocytes with swelling and dcgranulation; (b) in lung and bone marrow, the number of mastocytes is increased under hypovitaminosis A and there is also blood congestion and lipomatosis of bone marrow.

The authors give an interpretation of their results.

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