ABSTRACT
Mice were ovariectomized on the fourth day of gestation and the trophoblastic giant-cell transformation sought in blastocysts recovered from them after progesterone or corn oil had been injected or no treatment given.
The giant-cell transformation does not occur in blastocysts of untreated mice. It does take place after progesterone but not after corn oil injection on the fourth day.
The transformation does not occur after progesterone on the sixth, seventh and eighth days.
Progesterone injection on the fourth day is associated with growth of the blastocyst as a whole and also of its inner cell mass.
Copyright © 1967 by Company of Biologists
1967
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