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Model Systems in Drug Discovery
Model systems are central to the discovery and development of new and better treatments for human disease. This collection, first launched in 2015 with a special issue titled From Bench to Patient: Model Systems in Drug Discovery, guest edited by Matthew Breyer and Thomas Look, highlights the contribution of model systems to drug discovery and optimisation across multiple disease areas. It features Reviews and Research articles on the use of model systems to test or develop new therapies.
REVIEW
Sarah Campion; Amy Inselman; Belinda Hayes; Costanza Casiraghi; David Joseph; Fabrizio Facchinetti; Fabrizio Salomone; Georg Schmitt; Julia Hui; Karen Davis-Bruno; Karen Van Malderen; LaRonda Morford; Luc De Schaepdrijver; Lutz Wiesner; Stephanie Kourula; Suna Seo; Susan Laffan; Vijay Urmaliya; Connie Chen
25 April 2022
Doi:
10.1242/dmm.049065
RESOURCE ARTICLE
Agustin Resendiz-Sharpe; Roberta Peres da Silva; Elena Geib; Lore Vanderbeke; Laura Seldeslachts; Charlien Hupko; Matthias Brock; Katrien Lagrou; Greetje Vande Velde
30 March 2022
Doi:
10.1242/dmm.049165
RESEARCH ARTICLE
Nazia M. Alam; Robert M. Douglas; Glen T. Prusky
21 February 2022
Doi:
10.1242/dmm.048256
RESEARCH ARTICLE
Karmele Valencia; Cristina Sainz; Cristina Bértolo; Gabriel de Biurrun; Jackeline Agorreta; Arantza Azpilikueta; Marta Larrayoz; Graziella Bosco; Carolina Zandueta; Miriam Redrado; Esther Redín; Francisco Exposito; Diego Serrano; Mirari Echepare; Daniel Ajona; Ignacio Melero; Ruben Pio; Roman Thomas; Alfonso Calvo; Luis M. Montuenga
31 January 2022
Doi:
10.1242/dmm.049137
RESEARCH ARTICLE
Roger S. Smith; Igor Odintsov; Zebing Liu; Allan Jo-Weng Lui; Takuo Hayashi; Morana Vojnic; Yoshiyuki Suehara; Lukas Delasos; Marissa S. Mattar; Julija Hmeljak; Hillary A. Ramirez; Melissa Shaw; Gabrielle Bui; Alifiani B. Hartono; Eric Gladstone; Siddharth Kunte; Heather Magnan; Inna Khodos; Elisa De Stanchina; Michael P. La Quaglia; Jinjuan Yao; Marick Laé; Sean B. Lee; Lee Spraggon; Christine A. Pratilas; Marc Ladanyi; Romel Somwar
27 January 2022
Doi:
10.1242/dmm.047621
RESEARCH ARTICLE
Eva Habjan; Vien Q. T. Ho; James Gallant; Gunny van Stempvoort; Kin Ki Jim; Coen Kuijl; Daan P. Geerke; Wilbert Bitter; Alexander Speer
23 December 2021
Doi:
10.1242/dmm.049145
RESEARCH ARTICLE
Kamlesh Bhatt; Madhuri Bhagavathula; Sheetal Verma; Graham S. Timmins; Vojo P. Deretic; Jerrold J. Ellner; Padmini Salgame
26 October 2021
Doi:
10.1242/dmm.049018
PERSPECTIVE
James F. Amatruda
22 February 2021
Doi:
10.1242/dmm.048930
RESEARCH ARTICLE
Henrika Jodeleit; Paula Winkelmann; Janina Caesar; Sebastian Sterz; Lesca M. Holdt; Florian Beigel; Johannes Stallhofer; Simone Breiteneicher; Eckart Bartnik; Thomas Leeuw; Matthias Siebeck; Roswitha Gropp
21 January 2021
Doi:
10.1242/dmm.046995
RESEARCH ARTICLE
Lozan Sheriff; Reenam S. Khan; Raquel Saborano; Richard Wilkin; Nguyet-Thin Luu; Ulrich L. Gunther; Stefan G. Hubscher; Philip N. Newsome; Patricia F. Lalor
29 December 2020
Doi:
10.1242/dmm.046383
RESEARCH ARTICLE
Katie Lloyd; Stamatia Papoutsopoulou; Emily Smith; Philip Stegmaier; Francois Bergey; Lorna Morris; Madeleine Kittner; Hazel England; Dave Spiller; Mike H. R. White; Carrie A. Duckworth; Barry J. Campbell; Vladimir Poroikov; Vitor A. P. Martins dos Santos; Alexander Kel; Werner Muller; D. Mark Pritchard; Chris Probert; Michael D. Burkitt; The SysmedIBD Consortium
27 November 2020
Doi:
10.1242/dmm.044040
RESEARCH ARTICLE
Pingtao Tang; Jharna R. Das; Jinliang Li; Jing Yu; Patricio E. Ray
28 October 2020
Doi:
10.1242/dmm.045641
REVIEW
Alec M. DeSimone; Justin Cohen; Monkol Lek; Angela Lek
28 October 2020
Doi:
10.1242/dmm.046904
AT A GLANCE
Kim A. Caldwell; Corey W. Willicott; Guy A. Caldwell
26 October 2020
Doi:
10.1242/dmm.046110
RESEARCH ARTICLE REVIEW COMMONS TRANSFER
Angelino T. Tromp; Yuxi Zhao; Ilse Jongerius; Erik C. J. M. Heezius; Pauline Abrial; Maartje Ruyken; Jos A. G. van Strijp; Carla J. C. de Haas; András N. Spaan; Kok P. M. van Kessel; Thomas Henry; Pieter-Jan A. Haas
28 September 2020
Doi:
10.1242/dmm.045534
REVIEW
Anni K. Saralahti; Meri I. E. Uusi-Mäkelä; Mirja T. Niskanen; Mika Rämet
23 August 2020
Doi:
10.1242/dmm.045716
REVIEW
Jeffrey W. Santoso; Megan L. McCain
07 July 2020
Doi:
10.1242/dmm.044867
REVIEW
Mark L. Kovler; Chhinder P. Sodhi; David J. Hackam
24 June 2020
Doi:
10.1242/dmm.044388
REVIEW
Maaike van Putten; Erin M. Lloyd; Jessica C. de Greef; Vered Raz; Raffaella Willmann; Miranda D. Grounds
21 February 2020
Doi:
10.1242/dmm.043562
REVIEW
Raffaella Willmann; Joanne Lee; Cathy Turner; Kanneboyina Nagaraju; Annemieke Aartsma-Rus; Dominic J. Wells; Kathryn R. Wagner; Cristina Csimma; Volker Straub; Miranda D. Grounds; Annamaria De Luca
07 February 2020
Doi:
10.1242/dmm.042903
