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1-6 of 6
Keywords: miRNA
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Journal Articles
Journal:
Biology Open
Biol Open (2024) 13 (6): bio060308.
Published: 10 June 2024
... development, hormonal cues induce the regulation of different pathways, ultimately leading to differential transcription and expression of genes involved in this process, but also in the activation or inhibition of post-transcriptional mechanisms of regulation. However, the role of microRNAs (miRNAs...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2023) 12 (11): bio060096.
Published: 9 November 2023
...Alice Brown; Murray E. Selkirk; Peter Sarkies ABSTRACT Small non-coding RNAs such as microRNAs (miRNAs) are conserved across eukaryotes and play key roles in regulating gene expression. In many organisms, miRNAs are also secreted from cells, often encased within vesicles such as exosomes...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2021) 10 (6): bio058538.
Published: 29 June 2021
...Hongjin Liu; Qian Song; Hui Zhen; Hongkuan Deng; Bosheng Zhao; Zhonghong Cao ABSTRACT MicroRNAs (miRNAs) are a class of evolutionarily conserved small non-coding RNAs that regulate gene expression at the translation level in cell growth, proliferation and differentiation. In addition, some types...
Journal Articles
Journal:
Biology Open
Biol Open (2021) 10 (4): bio050930.
Published: 16 April 2021
...Xinhong Liu; Yu-Gang Li; Fang Tan; Jia Liu; Ruokun Yi; Xin Zhao ABSTRACT MicroRNAs (miRNAs) play essential roles in regulating bone formation and homeostasis. Genomic variations within miRNA target sites may therefore be important sources of genetic differences in osteoporosis risk. The function...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2018) 7 (4): bio029082.
Published: 18 April 2018
... of tilapia. Expression of miR-26a in the brain decreased significantly with increasing ammonia concentrations using stem-loop qPCR. To analyze the function of miRNA in vivo , miR-26a was stably knocked down with an antagomir in tilapia. Following ammonia challenge, miR-26a antagomir treatment significantly...
Journal Articles
Scott G. Daniel, Atlantis D. Russ, Kathryn M. Guthridge, Ammad I. Raina, Patricia S. Estes, Linda M. Parsons, Helena E. Richardson, Joyce A. Schroeder, Daniela C. Zarnescu
Journal:
Biology Open
Biol Open (2018) 7 (1): bio027391.
Published: 26 January 2018
..., asymmetric division, and proliferation control. Lgl's human orthologs, HUGL1 and HUGL2, are altered in human cancers, however, its mechanistic role as a tumor suppressor remains poorly understood. Based on a previously established connection between Lgl and Fragile X protein (FMRP), a miRNA-associated...
Includes: Supplementary data