... endoderm of the blastocyst, visceral endoderm of the early post-implantation embryo, as well as lateral plate mesoderm, developing heart, liver, lung and gonads. Here, we generate a novel Gata4 targeted allele used to generate both a Gata4 H2B-GFP transcriptional reporter and a Gata4 FLAG fusion protein...

...Lee B. Miles; Takamasa Mizoguchi; Yutaka Kikuchi; Heather Verkade ABSTRACT The zebrafish endoderm begins to develop at gastrulation stages as a monolayer of cells. The behaviour of the endoderm during gastrulation stages is well understood. However, knowledge of the morphogenic movements...

...David A. F. Loebel; Timothy F. Plageman, Jr; Theresa L. Tang; Vanessa J. Jones; Maria Muccioli; Patrick P. L. Tam ABSTRACT Early development of the gut endoderm and its subsequent remodeling for the formation of organ buds are accompanied by changes to epithelial cell shape and polarity. Members...

... increase on endoderm development, we have analyzed the mechanisms of endoderm formation in the catshark S. canicula , a species exhibiting telolecithal eggs and a distinct yolk sac. We show that in this species, endoderm markers are expressed in two distinct tissues, the deep mesenchyme, a mesenchymal...

... specification was recently identified in zebrafish; however, its underlying cellular mechanisms are unknown. Here, we present two cellular mechanisms by which Wnt/β-catenin signaling regulates liver specification. First, using lineage tracing we show that ectopic hepatoblasts, which form in the endoderm...