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Keywords: dMyc
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Journal Articles
Biol Open (2020) 9 (3): bio048850.
Published: 24 March 2020
... and degradation of the extracellular matrix, which are essential properties of cell invasion. Further assay found that sal / SALL4 promoted cell invasion via dMyc-JNK signaling. Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway through suppressing matrix metalloprotease 1 , or basket can achieve...
Includes: Supplementary data
Journal Articles
Biol Open (2017) 6 (8): 1229–1234.
Published: 22 June 2017
... synthesis induced by two known stimulators of mRNA translation – the nutrient/TORC1 kinase pathway and the transcription factor dMyc. We also use the assay to describe how protein synthesis changes through larval development and in response to two environmental stressors – hypoxia and heat shock. We propose...
Includes: Supplementary data
Journal Articles
Biol Open (2013) 2 (1): 1–9.
Published: 23 October 2012
... itself leads to reduction in its abundance. We show here that dMyc binds to the miR-308 locus and increases its expression. Using our gain-of-function approach, we show that an increase in miR-308 causes a destabilization of dMyc mRNA and reduced dMyc protein levels. In vivo knockdown of miR-308...