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Keywords: bHLH
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Journal Articles

Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless

Open Access
Laura Tamberg, Mari Sepp, Tõnis Timmusk, Mari Palgi
Journal: Biology Open
Biol Open (2015) 4 (12): 1762–1771.
https://doi.org/10.1242/bio.014696
Published: 30 November 2015
... orthologue daughterless allows the generation of Drosophila models for research into Pitt-Hopkins syndrome. Pitt-Hopkins syndrome Drosophila melanogaster Intellectual disability Daughterless bHLH Nervous system Pitt-Hopkins syndrome (PTHS, OMIM #610954) is a rare human disorder...
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Includes: Supplementary data
Journal Articles

Complex regulation controls Neurogenin3 proteolysis

Open Access
Ryan Roark, Laura Itzhaki, Anna Philpott
Journal: Biology Open
Biol Open (2012) 1 (12): 1264–1272.
https://doi.org/10.1242/bio.20121750
Published: 16 October 2012
..., a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol. Cell. Neurosci. 8 , 221 – 241 . 10.1006/mcne.1996.0060 Thrower J. S. , Hoffman L...
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