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Journal Articles

Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

Javier Gilbert-Jaramillo, Ujang Purnama, Zoltán Molnár, William S. James
Journal: Biology Open
Biol Open (2023) 12 (4): bio059889.
https://doi.org/10.1242/bio.059889
Published: 24 April 2023
... metabolism by Zika virus (ZIKV) to support its replication may contribute to damage in the developing fetal brain. Here, we showed that ZIKV replicates differently in two glycolytically distinct pools of cortical progenitors derived from human induced pluripotent stem cells (hiPSCs), which resemble...
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Includes: Supplementary data