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Keywords: Wound healing
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Journal Articles
Biol Open (2021) 10 (1): bio055996.
Published: 25 January 2021
... Yorkie-induced endoreplication and cell fusion. As a result, wound healing is perturbed when focal adhesion genes are knocked down. These findings show that conserved focal adhesion signaling is required to initiate wound-induced polyploid cell growth. We first examined the expression and...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (5): bio048629.
Published: 03 May 2020
... connected and the dysregulation of mitochondrial dynamics is linked to several human diseases. In this work, we investigated the role of mitochondrial dynamics in wound healing in the Drosophila embryonic epidermis. Mutants for mitochondrial fusion and fission proteins fail to close their wounds, indicating...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (7): bio043711.
Published: 18 July 2019
...Joshua D. Currie; Lidia Grosser; Prayag Murawala; Maritta Schuez; Martin Michel; Elly M. Tanaka; Tatiana Sandoval-Guzmán ABSTRACT The heterogeneous properties of dermal cell populations have been posited to contribute toward fibrotic, imperfect wound healing in mammals. Here we characterize an...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (1): bio026187.
Published: 17 January 2018
...Yan Liu; Sandeep Dhall; Anthony Castro; Alex Chan; Raquelle Alamat; Manuela Martins-Green ABSTRACT Wound healing is a complex process that involves sequential phases that overlap in time and space and affect each other dynamically at the gene and protein levels. We previously showed that insulin...
Journal Articles
Biol Open (2016) 5 (3): 211–219.
Published: 21 January 2016
...Jie Zhou; Xipeng Zhang; Pengfei Liang; Licheng Ren; Jizhang Zeng; Minghua Zhang; Pihong Zhang; Xiaoyuan Huang ABSTRACT Our previous study has suggested that downregulated microRNA (miR)-29a in denatured dermis might be involved in burn wound healing. However, the exact role of miR-29a in healing of...
Journal Articles
Biol Open (2012) 1 (12): 1169–1177.
Published: 20 September 2012
... undetectable until several days later. This “cell type traffic” regulation ensures proper healing of the wound, as disruptions of the regulation could either cause delay of wound healing or result in hypertrophic scars. TGFβ3 is the critical traffic controller that selectively halts migration of the dermal...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (10): 937–948.
Published: 27 July 2012
... denervated limb that will not regenerate a limb, and 3) an innervated limb that will regenerate a limb. Early, histological and transcriptional changes were similar between the injury types, presumably because a common wound-healing program is employed across anatomical locations. However, some transcripts...
Includes: Supplementary data