...Nydia Tejeda-Muñoz; Yagmur Azbazdar; Eric A. Sosa; Julia Monka; Pu-Sheng Wei; Grace Binder; Kuo-Ching Mei; Yerbol Z. Kurmangaliyev; Edward M. De Robertis ABSTRACT Recent research has shown that membrane trafficking plays an important role in canonical Wnt signaling through sequestration of the β...

... in the blastocyst and increases cells expressing CDX2. Actions of activin A to promote blastocyst development may involve its role in promoting trophectoderm formation. Furthermore, results demonstrate the negative role of canonical WNT signaling in cattle for pluripotency marker expression in ESC and in formation...

.... Caspase 1 inhibitor, caspase 3 inhibitor, or pan-caspase inhibitor Z-VAD-FMK treatment blocked apoptosis, prevented regeneration, and suppressed branchial sac growth and function. A pharmacological screen and siRNA-mediated gene knockdown indicated that regeneration requires canonical Wnt signaling. Wnt3a...

... ). Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels . Curr. Biol.   7 , 940 - 949 . 10.1016/S0960-9822(06)00413-1 Angers , S. and Moon , R. T. ( 2009 ). Proximal events in Wnt signal transduction . Nat. Rev. Mol. Cell Biol...

...-catenin, which has a central role in Wnt signaling. In A172 human glioblastoma cells, lithium treatment caused a surprising increase in phospho-Ser33/Ser37-β-catenin, which was quantified using an antibody-coupled capillary electrophoresis method. The β-catenin hyperphosphorylation was unaffected by p53...

... guidance Wnt signaling Neurons The HSN neuron of Caenorhabditis elegans extends short neurites in different directions immediately after the animal hatches. These neurites, which dynamically extend and retract filopodia, become restricted to the ventral side of the neuron where a leading edge...

... in any medium provided that the original work is properly attributed. Neural stem cells Wnt signaling ES cells Neurosphere assay Neural stem cells (NSCs), which give rise to all neuronal and glial progenitors of the nervous system, are present throughout development, from embryo to adult...