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Keywords: Wingless
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Journal Articles
Journal:
Biology Open
Biol Open (2021) 10 (12): bio058892.
Published: 2 December 2021
... of Wnt/Wingless signalling. We observed a dominant loss of wing margin bristles and Senseless expression in Arf6 mutant flies, phenotypes characteristic of a defect in high level Wingless signalling. In contrast to previous findings, we show that Arf6 is required downstream of Armadillo/β-catenin...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2017) 6 (11): 1664–1671.
Published: 15 November 2017
... toxic in non-neural cells, neurosecretory and epithelial cell types in particular. This form of toxicity includes the aberrant signaling by Wingless morphogen leading to the eventual activation of Caspase 3. Preventing Caspase 3 activation by means of p53 keeps epithelial cells from elimination...
Includes: Supplementary data