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Keywords: WNT signaling
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Journal Articles
Biol Open (2021) 10 (11): bio058669.
Published: 29 November 2021
... in the blastocyst and increases cells expressing CDX2. Actions of activin A to promote blastocyst development may involve its role in promoting trophectoderm formation. Furthermore, results demonstrate the negative role of canonical WNT signaling in cattle for pluripotency marker expression in ESC and in formation...
Journal Articles
Biol Open (2021) 10 (4): bio058526.
Published: 23 April 2021
.... Caspase 1 inhibitor, caspase 3 inhibitor, or pan-caspase inhibitor Z-VAD-FMK treatment blocked apoptosis, prevented regeneration, and suppressed branchial sac growth and function. A pharmacological screen and siRNA-mediated gene knockdown indicated that regeneration requires canonical Wnt signaling. Wnt3a...
Journal Articles
Biol Open (2018) 7 (11): bio033001.
Published: 02 November 2018
... transmembrane tyrosine kinases promote signaling via the Wnt-PCP pathway and suppress beta-catenin-dependent Wnt signaling ( Green et al., 2014 ; Mikels and Nusse, 2006 ; Oishi et al., 2003 ). Mice, frogs and zebrafish mutant for Ror2 display strong PCP phenotypes characterized by defects in convergent...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (1): bio030874.
Published: 26 January 2018
...-catenin, which has a central role in Wnt signaling. In A172 human glioblastoma cells, lithium treatment caused a surprising increase in phospho-Ser33/Ser37-β-catenin, which was quantified using an antibody-coupled capillary electrophoresis method. The β-catenin hyperphosphorylation was unaffected by p53...
Includes: Supplementary data
Journal Articles
Biol Open (2013) 2 (12): 1300–1312.
Published: 23 October 2013
.../licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Caenorhabditis elegans DCC receptor Netrin Stochastic Process UNC-6 Axon guidance Wnt signaling Neurons The HSN neuron...
Journal Articles
Biol Open (2013) 2 (8): 812–821.
Published: 20 June 2013
... and reproduction in any medium provided that the original work is properly attributed. Neural stem cells Wnt signaling ES cells Neurosphere assay Single NSCs can be isolated from the adult or embryonic brain, and subsequently expanded in vitro to form clonal floating spheres, called neurospheres...
Includes: Supplementary data