... and intracellular structure. We identified a structural phenotype in the pre-synaptic regions of these damaged hair cells that persists for four weeks after noise exposure, and demonstrates a specific dysregulation of the synaptic vesicle recycling pathway. We show evidence of a failure in regeneration of vesicles...

... could show a similar mislocalization than amino acid permeases in Δ glo3 Δ erg3 . The plasma membrane ATPase Pma1 was shown to be transported to the plasma membrane in ergosterol- and sphingolipid- rich secretory vesicles ( Surma et al., 2011 ). Yet, interfering with ergosterol synthesis did not cause...