... acid (IAA), the auxin most commonly used to trigger AID in worms, functions through the conserved IRE-1/XBP-1 branch of the Unfolded Protein Response (UPR) to promote resistance to endoplasmic reticulum (ER) stress. Because the UPR not only plays a central role in restoring ER homeostasis, but also...

... ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. C. elegans molting larvae amyloid cuticle ABU/PQN innate immunity unfolded protein response Ecdysozoa, the clade of animals defined by the presence...