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Keywords: Ubiquitination
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Journal Articles
Biol Open (2018) 7 (12): bio037366.
Published: 14 December 2018
...Qingya Shen; Zhiyu Qiu; Wenping Wu; Jimin Zheng; Zongchao Jia ABSTRACT Phosphoenolpyruvate carboxykinase (PEPCK1) is ubiquitinated by E3 ubiquitin ligase UBR5, which was thought to be facilitated by the acetylation of Lys70, Lys71 and Lys594 in PEPCK1. Here, we made a series of UBR5 HECT domain...
Includes: Supplementary data
Journal Articles
Biol Open (2017) 6 (10): 1404–1415.
Published: 10 August 2017
... defined. Vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor receptor 2 (VEGFR2) regulate signal transduction and angiogenesis, but how signaling and proteolysis is regulated is not well understood. Here, we provide evidence that a pathway requiring the E1 ubiquitin...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (7): 669–676.
Published: 27 June 2014
...Sarah G. Hainline; Jamie L. Rickmyre; Leif R. Neitzel; Laura A. Lee; Ethan Lee ABSTRACT The Anaphase-Promoting Complex (APC) is a multi-subunit E3 ubiquitin ligase that coordinates progression through the cell cycle by temporally and spatially promoting the degradation of key proteins. Many...
Includes: Supplementary data
Journal Articles