...Suzuko Kinoshita; Kazuki Takarada; Yuriko Kinoshita; Yoshihiro H. Inoue ABSTRACT Mechanisms of cancer cell recognition and elimination by the innate immune system remains unclear. The immune signaling pathways are activated in the fat body to suppress the tumor growth in mxc mbn1 hematopoietic...

...Stefanie Stickel; Tin Tin Su ABSTRACT An emerging interest in oncology is to tailor treatment to particular cancer genotypes, i.e. oncogenic mutations present in the tumor, and not the tissue of cancer incidence. Integral to such a practice is the idea that the same oncogenic mutation(s) produces...

...Thomas Hauling; Robert Krautz; Robert Markus; Anne Volkenhoff; Lucie Kucerova; Ulrich Theopold ABSTRACT Our goal is to characterize the innate immune response against the early stage of tumor development. For this, animal models where genetic changes in specific cells and tissues can be performed...