...María Nazareth González Alvarado; Jessica Aprato ABSTRACT Sox8 is a transcription factor that belongs to the Sox family of high-mobility-group domain containing proteins and is closely related to Sox9 and Sox10. During prenatal development, Sox8 is expressed in several ectoderm-, endoderm...

... attributed. Summary: Parallel measurements of hypoxia inducible factor protein and mRNA support post-translational protein stabilization rather than new transcription in the initial response of fish to low oxygen. Oxygen Teleost fish Transcription factor Individual variation Greater...

...Roman Zug ABSTRACT Many human birth defects and neurodevelopmental disorders are caused by loss-of-function mutations in a single copy of transcription factor (TF) and chromatin regulator genes. Although this dosage sensitivity has long been known, how and why haploinsufficiency (HI...

... tegmental area (VTA) Substantia nigra pars reticulata (SNpr) Midbrain Dopaminergic neuron Hindbrain Rhombomere 1 Transcription factor Gata Tal Scl Brain development Mouse The mammalian midbrain and hindbrain contain neuronal populations that control motivation, motor and sensory function...