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Keywords: Toll pathway
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Journal Articles

SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cells

Tack-Jin Yoo, Myoung Sup Shim, Jeyoung Bang, Jin-Hong Kim, Byeong Jae Lee
Journal: Biology Open
Biol Open (2022) 11 (8): bio059295.
https://doi.org/10.1242/bio.059295
Published: 1 August 2022
... that the activation of AMP expression is regulated by both immune deficiency (IMD) and the Toll pathway. Double knockdown of the upstream genes of each pathway with SPS1 showed that the peptidoglycan recognition protein-LC (PGRP-LC) and Toll genes are targeted by SPS1 for regulating these pathways. We also found...
View articletitled, SPS1 deficiency-triggered PGRP-LC and Toll expression controls innate immunity in Drosophila S2 cells
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Includes: Supplementary data