...Stephanie A. Ross; Christine Waters-Banker; Andrew Sawatsky; Timothy R. Leonard; Walter Herzog ABSTRACT Skeletal muscles and the tendons that attach them to bone are structurally complex and deform non-uniformly during contraction. While these tissue deformations dictate force production during...

...Yasuyuki Morita; Toshihiro Sato; Kouji Higashiura; Yusho Hirano; Fuga Matsubara; Kanau Oshima; Koji Niwa; Yuhki Toku; Guanbin Song; Qing Luo; Yang Ju ABSTRACT In tendon tissue engineering, mechanical stimulus-induced differentiation is one of the most attractive techniques for stem cell-to-tenocyte...

.... In the developing Drosophila leg, tendon-like connective tissue arises from clusters of epithelial cells that invaginate into the leg cavity and then elongate to form internal tube-shape structures along which muscle precursors are distributed. Here we show that stripe-positive appendicular precursors of tendon...

... remains elusive. Our previous analysis indicated that Slit cleavage is essential to immobilize the active Slit-N at the tendon cell surfaces, mediating the arrest of muscle elongation. In an attempt to identify the protease required for Slit cleavage we performed an RNAi-based assay in the ectoderm...