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Keywords: Tauopathy
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Journal Articles

A larval zebrafish model of traumatic brain injury: optimizing the dose of neurotrauma for discovery of treatments and aetiology

Laszlo F. Locskai, Taylor Gill, Samantha A. W. Tan, Alexander H. Burton, Hadeel Alyenbaawi, Edward A. Burton, W. Ted Allison
Journal: Biology Open
Biol Open (2025) 14 (2): bio060601.
https://doi.org/10.1242/bio.060601
Published: 12 February 2025
..., distribution and reproduction in any medium provided that the original work is properly attributed. Summary: Epilepsy Neurodegeneration Neurotrauma Post-traumatic seizures Tauopathy Traumatic brain injury Canadian Institutes of Health Research (CIHR) Alzheimer Society...
View articletitled, A larval zebrafish model of traumatic brain injury: optimizing the dose of neurotrauma for discovery of treatments and aetiology
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Includes: Supplementary data
Journal Articles

Human TTBK1, TTBK2 and MARK1 kinase toxicity in Drosophila melanogaster is exacerbated by co-expression of human Tau

Josefin Fernius, Annika Starkenberg, Malgorzata Pokrzywa, Stefan Thor
Journal: Biology Open
Biol Open (2017) 6 (7): 1013–1023.
https://doi.org/10.1242/bio.022749
Published: 15 July 2017
... combinatorial toxicity of MARK with Nuak1. Summary: Tau hyper-phosphorylation has been linked to toxicity, but the Tau isoforms, kinases and residues remain unclear. Using the Drosophila model, we find evidence for involvement of TTBK and MARK kinases. Tauopathy Neuronal toxicity Drosophila...
View articletitled, Human TTBK1, TTBK2 and MARK1 kinase toxicity in Drosophila melanogaster is exacerbated by co-expression of human Tau
Open the PDF for Human TTBK1, TTBK2 and MARK1 kinase toxicity in Drosophila melanogaster is exacerbated by co-expression of human Tau in another window
Includes: Supplementary data