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Keywords: TWIST1
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Journal Articles
Biol Open (2024) 13 (12): bio061790.
Published: 9 December 2024
... the induction of EMT. Unfortunately, current inducible EMT models still present unmet needs. Therefore, we aimed to establish an inducible EMT model in MCF10A cells, a spontaneously immortalized human fibrocystic mammary cell line, by manipulating the expression of mouse Twist1 (mTwist1). In this study, we...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (9): 1216–1228.
Published: 11 July 2016
... of the transcription factor Twist1 and here utilize it to characterize the timing and dynamics of intercellular adhesion, proliferation and migration during dissemination. Surprisingly, Twist1 + epithelium displayed extensive intercellular junctions, and Twist1 – luminal epithelial cells could still adhere...
Includes: Supplementary data