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Keywords: TALEN
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Journal Articles
Biol Open (2015) 4 (2): 180–185.
Published: 16 January 2015
...Keisuke Nakajima; Yoshio Yaoita ABSTRACT Zinc-finger nucleases, transcription activator-like effector nucleases (TALENs) and the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins) system are potentially powerful tools for producing tailor-made knockout...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Biol Open (2013) 2 (4): 363–367.
Published: 12 February 2013
... (TALENs) can induce a targeted DNA double-strand break at the specific target genomic locus, leading to the frameshift-mediated gene disruption. However, the assays for their activity on the endogenous genomic loci remain limited. Herein, we describe a versatile modified lacZ assay to detect frameshifts...
Includes: Supplementary data