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Keywords: Substrate rigidity
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Journal Articles

Soft substrate maintains proliferative and adipogenic differentiation potential of human mesenchymal stem cells on long-term expansion by delaying senescence

Sanjay Kumar Kureel, Pankaj Mogha, Akshada Khadpekar, Vardhman Kumar, Rohit Joshi, Siddhartha Das, Jayesh Bellare, Abhijit Majumder
Journal: Biology Open
Biol Open (2019) 8 (4): bio039453.
https://doi.org/10.1242/bio.039453
Published: 26 April 2019
... by delaying senescence when expanded in vitro on soft polyacrilamide gel. Cell mechanics Mesenchymal stem cells Senescence Stemness Substrate rigidity Human mesenchymal stem cells (hMSCs), due to their multi-lineage differentiation potential, immuno-suppressive capability, and immuno...
View articletitled, Soft substrate maintains proliferative and adipogenic differentiation potential of human mesenchymal stem cells on long-term expansion by delaying senescence
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Includes: Supplementary data