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Keywords: Stem cell niche
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Journal Articles

Notch signaling governs the expression of glypican Dally to define the stem cell niche

Songhua Zhao, Chan Wu, Zhiyang Gao, Xin Li, Zheng Guo, Zhaohui Wang
Journal: Biology Open
Biol Open (2020) 9 (1): bio047696.
https://doi.org/10.1242/bio.047696
Published: 10 January 2020
... in the niche for the maintenance of germline stem cells (GSCs) via short-range BMP signaling in ovary. However, the regulatory mechanism of glypican pattern in the ovarian stem cell niche remains elusive. Our current data demonstrate that the Notch pathway is genetically upstream of Dally and its function...
View articletitled, Notch signaling governs the expression of glypican Dally to define the stem cell niche
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Includes: Supplementary data
Journal Articles

Cell tracking in vitro reveals that the extracellular matrix glycoprotein Tenascin-C modulates cell cycle length and differentiation in neural stem/progenitor cells of the developing mouse spinal cord

Marcus May, Bernd Denecke, Timm Schroeder, Magdalena Götz, Andreas Faissner
Journal: Biology Open
Biol Open (2018) 7 (7): bio027730.
https://doi.org/10.1242/bio.027730
Published: 25 July 2018
... by the removal of FGF2 and EGF glial differentiation was enhanced. We conclude that the constituent of the stem cell niche Tnc contributes to preserve stemness of NPCs. For the purpose to analyse the influence of the mitogens EGF and FGF2 on WT and Tnc KO spinal cord progenitors of the different generations...
View articletitled, Cell tracking in vitro reveals that the extracellular matrix glycoprotein Tenascin-C modulates cell cycle length and differentiation in neural stem/progenitor cells of the developing mouse spinal cord
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Includes: Supplementary data
Journal Articles

Cellular population dynamics control the robustness of the stem cell niche

Adam L. MacLean, Paul D. W. Kirk, Michael P. H. Stumpf
Journal: Biology Open
Biol Open (2015) 4 (11): 1420–1426.
https://doi.org/10.1242/bio.013714
Published: 9 October 2015
...Adam L. MacLean; Paul D. W. Kirk; Michael P. H. Stumpf ABSTRACT Within populations of cells, fate decisions are controlled by an indeterminate combination of cell-intrinsic and cell-extrinsic factors. In the case of stem cells, the stem cell niche is believed to maintain ‘stemness’ through...
View articletitled, Cellular population dynamics control the robustness of the stem cell niche
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Includes: Supplementary data