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Keywords: Spastin
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Journal Articles
Yongjun Fan, Gautam Wali, Ratneswary Sutharsan, Bernadette Bellette, Denis I. Crane, Carolyn M. Sue, Alan Mackay-Sim
Journal:
Biology Open
Biol Open (2014) 3 (6): 494–502.
Published: 23 May 2014
..., for which there are no treatments targeted at the underlying pathophysiology. Mutations in spastin are a common cause of HSP. Spastin is a microtubule-severing protein whose mutation in mouse causes defective axonal transport. In human patient-derived olfactory neurosphere-derived (ONS) cells, spastin...
Includes: Multimedia, Supplementary data
