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Keywords: Sec63
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Journal Articles
Anke Ziska, Jörg Tatzelt, Johanna Dudek, Adrienne W. Paton, James C. Paton, Richard Zimmermann, Sarah Haßdenteufel
Journal:
Biology Open
Biol Open (2019) 8 (3): bio040691.
Published: 5 March 2019
... membrane resident Hsp40-type co-chaperone Sec63 as well as the ER lumenal Hsp70-type chaperone BiP were proposed to facilitate channel opening in a precursor-specific fashion. Here, we report on their rules of engagement in ER import of the prion protein (PrP) by addressing sixteen PrP-related variants...
Includes: Supplementary data
