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Keywords: Screen
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Journal Articles
Journal:
Biology Open
Biol Open (2022) 11 (12): bio059695.
Published: 19 December 2022
... and incompletely understood. To shed light on this mystery, we performed a genome-wide CRISPR-Cas9 screen to systematically identify regulators of cancer resistance to the soluble short chain ceramide, C6 ceramide (C6-Cer). Our results reveal a complex landscape of genetic modifiers of C6-Cer toxicity, including...
Includes: Supplementary data
