..., leading to unanticipated outcomes in the behavior and fate of such cells. Functional communication of Cdc2 with Sty1 is known to be an integral part of the cellular response to aberrant Cdc2 activity in S. pombe . Our results show that cross-talk between Cdc2 and Sty1, and the consequent Sty1-dependent...

... studied. We present evidence that CDK activity can regulate the extent of MAPK activation in Schizosaccharomyces pombe cells. We show that increasing or decreasing mitotic CDK (Cdc2) activity in S. pombe cells can affect the activation of stress responsive MAPK (Spc1) even in the absence of stress stimuli...

..., distribution and reproduction in any medium provided that the original work is properly attributed. TOR S. pombe Cell growth Chronological lifespan Oxidative stress S6 kinase Sck2 Protein translation Lifespan is not invariably fixed but determined by genetic and environmental factors...

... by The Company of Biologists Ltd 2012 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License ( http://creativecommons.org/licenses/by-nc-sa/3.0/ ). Gad8 Maf1 S6 S6K TOR S. pombe Strains used in this study...