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Keywords: RNA-Seq
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Journal Articles
Biol Open (2023) 12 (11): bio059778.
Published: 29 November 2023
..., seizures, intellectual disability, nonverbal status, postnatal microcephaly, and ataxia. To define transcriptome signatures of NHE6 LoF, we conducted in-depth RNA-sequencing (RNA-seq) analysis on a haploid NHE6 null cell model. CRIPSR/Cas9 genome editing introduced multiple LoF mutations into SLC9A6...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Biol Open (2019) 8 (11): bio046789.
Published: 12 November 2019
... generation RNA sequencing (RNA-seq) the transcriptome of germline stem cell (GSC)-like cells isolated from bag of marbles ( bam ) mutant Drosophila ovaries and compared it to the transcriptome of germ line cells isolated from wild-type ovaries. We have complemented this dataset by utilizing an RNA...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (5): bio043372.
Published: 30 May 2019
... conjugated onto another protein as a single unit. Here, to explore whether an organismal defense is mounted against unanchored chains, we conducted RNA-Seq analyses to examine the transcriptomic impact of free poly-ubiquitin in the fly. We found ∼90 transcripts whose expression is altered in the presence...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (4): bio039917.
Published: 23 April 2019
.... Summary: Comparative transcriptome analyses of cloned and in vivo fertilized pre-implantation embryos: transcriptional defects and reprogramming barriers in porcine somatic cell nuclear reprogramming. Pig Pre-implantation embryos RNA-seq Somatic cell nuclear transfer Somatic cell...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (3): bio038422.
Published: 4 March 2019
...-temporal-resolution RNA-seq databases and the results showed that temporal collinearity is not supported, which is consistent with our previous data from allotetraploid X enopus laevis . Because the temporal collinearity hypothesis implicitly assumes the collinear order of gene activation, not mRNA...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (8): 1134–1141.
Published: 21 July 2016
... during early zebrafish development has long-term consequences that affect immune gene expression and regulation in adulthood. Chronic stress Glucocorticoid Developmental programming Immune system RNA-seq Zebrafish Chronic psychosocial stress contributes significantly to a wide variety...
Includes: Supplementary data