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Keywords: Protein synthesis
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Journal Articles

Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila

Open Access
Hye Jin Hwang, Rachel T. Cox
Journal: Biology Open
Biol Open (2024) 13 (11): bio061697.
https://doi.org/10.1242/bio.061697
Published: 25 November 2024
... nutrient conditions that adversely affect oogenesis, thus making analysis challenging. Cycloheximide is a widely used compound that binds to and stalls the ribosome, therefore reducing protein synthesis. As egg production is a highly nutrient-dependent process, we developed a method to feed female...
View articletitled, Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila
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Includes: Supplementary data
Journal Articles

Investigation of protein synthesis in Drosophila larvae using puromycin labelling

Open Access
Lisa P. Deliu, Abhishek Ghosh, Savraj S. Grewal
Journal: Biology Open
Biol Open (2017) 6 (8): 1229–1234.
https://doi.org/10.1242/bio.026294
Published: 22 June 2017
...Lisa P. Deliu; Abhishek Ghosh; Savraj S. Grewal ABSTRACT Translational control of gene expression is an important regulator of growth, homeostasis and aging in Drosophila . The ability to measure changes in protein synthesis in response to genetic and environmental cues is therefore important...
View articletitled, Investigation of protein synthesis in Drosophila larvae using puromycin labelling
Open the PDF for Investigation of protein synthesis in Drosophila larvae using puromycin labelling in another window
Includes: Supplementary data