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Keywords: Prostate cancer
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Journal Articles

Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro

Hung Wei Lai, Moe Kasai, Shinkuro Yamamoto, Hideo Fukuhara, Takashi Karashima, Atsuhi Kurabayashi, Mutsuo Furihata, Kazuhiro Hanazaki, Keiji Inoue, Shun-ichiro Ogura
Journal: Biology Open
Biol Open (2023) 12 (4): bio059615.
https://doi.org/10.1242/bio.059615
Published: 6 April 2023
.... A prostate cancer cell line, PC3, was used in this study. To investigate the Warburg effect effect and CSC-like characteristics in prostate cancer, we measured the expression levels of glycolysis and OXPHOS-related genes, and performed spheroid forming, cell viability and various glycolysis and OXPHOS-assays...
View article titled, Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in <span class="search-highlight">prostate</span> <span class="search-highlight">cancer</span> in vitro
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Includes: Supplementary data
Journal Articles

A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls

Morgan Thompson, Noemi Sarabia Feria, Ally Yoshioka, Eugene Tu, Fehmi Civitci, Suzanne Estes, Josiah T. Wagner
Journal: Biology Open
Biol Open (2021) 10 (3): bio057398.
https://doi.org/10.1242/bio.057398
Published: 26 March 2021
...Morgan Thompson; Noemi Sarabia Feria; Ally Yoshioka; Eugene Tu; Fehmi Civitci; Suzanne Estes; Josiah T. Wagner ABSTRACT Current methods for non-invasive prostate cancer (PrCa) detection have a high false-positive rate and often result in unnecessary biopsies. Previous work has suggested...
View article titled, A Caenorhabditis elegans behavioral assay distinguishes early stage <span class="search-highlight">prostate</span> <span class="search-highlight">cancer</span> patient urine from controls
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Includes: Supplementary data
Journal Articles

F-actin reorganization by V-ATPase inhibition in prostate cancer

Yamhilette Licon-Munoz, Vera Michel, Colleen A. Fordyce, Karlett J. Parra
Journal: Biology Open
Biol Open (2017) 6 (11): 1734–1744.
https://doi.org/10.1242/bio.028837
Published: 16 October 2017
... studied V-ATPase in the prostate cancer (PCa) cell line PC-3, which has characteristics of highly metastatic PCa. V-ATPase inhibitors impaired endo-lysosomal pH, vesicle trafficking, migration, and invasion. V-ATPase accrual in the Golgi and recycling endosomes suggests that traffic of internalized...
View article titled, F-actin reorganization by V-ATPase inhibition in <span class="search-highlight">prostate</span> <span class="search-highlight">cancer</span>
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Includes: Supplementary data
Journal Articles

EphA receptors regulate prostate cancer cell dissemination through Vav2–RhoA mediated cell–cell repulsion

Jennifer Batson, Lucy Maccarthy-Morrogh, Amy Archer, Helen Tanton, Catherine D. Nobes
Journal: Biology Open
Biol Open (2014) 3 (6): 453–462.
https://doi.org/10.1242/bio.20146601
Published: 2 May 2014
...Jennifer Batson; Lucy Maccarthy-Morrogh; Amy Archer; Helen Tanton; Catherine D. Nobes ABSTRACT Metastatic prostate cancer cells display EphB receptor-mediated attraction when they contact stromal fibroblasts but EphA-driven repulsion when they contact one another. The impact of these ‘social...
View article titled, EphA receptors regulate <span class="search-highlight">prostate</span> <span class="search-highlight">cancer</span> cell dissemination through Vav2–RhoA mediated cell–cell repulsion
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Includes: Multimedia, Supplementary data