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Keywords: Polycomb
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Journal Articles
Biol Open (2023) 12 (6): bio059955.
Published: 7 June 2023
...Rachel E. Cherney; Christine A. Mills; Laura E. Herring; Aki K. Braceros; J. Mauro Calabrese ABSTRACT The Polycomb Repressive Complex 2 (PRC2) is a conserved enzyme that tri-methylates Lysine 27 on Histone 3 (H3K27me3) to promote gene silencing. PRC2 is remarkably responsive to the expression...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (8): bio043638.
Published: 23 August 2019
...Priscilla Tang; Kamelia Miri; Susannah Varmuza ABSTRACT Stem/progenitor cells are maintained by a chromatin environment, mediated in part by Polycomb group (PcG) proteins, which depress differentiation. The trophoblast-specific PcG protein SFMBT2 is known to be required for maintenance...
Includes: Supplementary data
Journal Articles
Biol Open (2015) 4 (9): 1109–1121.
Published: 14 August 2015
...Emilie Le Goff; Camille Martinand-Mari; Marianne Martin; Jérôme Feuillard; Yvan Boublik; Nelly Godefroy; Paul Mangeat; Stephen Baghdiguian; Giacomo Cavalli ABSTRACT The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the spatial...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (6): 597–606.
Published: 9 May 2012
... in primary spermatocytes. Bromodomain proteins are able to recognise and bind acetylated histones and non-histone proteins. We generated tbrd-1 mutant flies and observed that function of tBRD-1 is required for male fertility. tBRD-1 partially colocalised with tTAFs, TAF1 and Polycomb to a Fibrillarin...