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Keywords: Pluripotency
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Journal Articles
Biol Open (2021) 10 (11): bio058669.
Published: 29 November 2021
...Yao Xiao; Froylan Sosa; Pablo J. Ross; Kenneth E. Diffenderfer; Peter J. Hansen ABSTRACT Bovine embryonic stem cells (ESC) have features associated with the primed pluripotent state including low expression of one of the core pluripotency transcription factors, NANOG. It has been reported...
Journal Articles
Biol Open (2021) 10 (10): bio058756.
Published: 01 November 2021
...Viju Vijayan Pillai; Prasanthi P. Koganti; Tiffany G. Kei; Shailesh Gurung; W. Ronald Butler; Vimal Selvaraj ABSTRACT Although derivation of naïve bovine embryonic stem cells is unachieved, the possibility for generation of bovine induced pluripotent stem cells (biPSCs) has been generally reported...
Includes: Supplementary data
Journal Articles
Biol Open (2021) 10 (7): bio058544.
Published: 14 July 2021
... to cell differentiation did not show a large change in expression. On the other hand, genes related to pluripotency, such as Oct4 and Sox2 , showed a twofold increase in expression upon application of 60 MPa hydrostatic pressure for 10 min. Although these changes did not persist after overnight culture...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (11): bio046367.
Published: 02 December 2019
...Antonio Barral; Isabel Rollan; Hector Sanchez-Iranzo; Wajid Jawaid; Claudio Badia-Careaga; Sergio Menchero; Manuel J. Gomez; Carlos Torroja; Fatima Sanchez-Cabo; Berthold Göttgens; Miguel Manzanares; Julio Sainz de Aja ABSTRACT Pluripotency is regulated by a network of transcription factors...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (11): bio034355.
Published: 01 November 2018
...Ade Kallas-Kivi; Annika Trei; Artjom Stepanjuk; Katrin Ruisu; Keiu Kask; Margus Pooga; Toivo Maimets ABSTRACT The maintenance of the pluripotency of human embryonic stem (hES) cells requires special conditions for culturing. These conditions include specific growth factors containing media...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (8): bio033282.
Published: 17 August 2018
...; Giovanna Lazzari; Poul Hyttel; Hendrik G. Stunnenberg; Martijn Huynen; Roger A. Pedersen; Andras Dinnyes ABSTRACT During early mammalian development, transient pools of pluripotent cells emerge that can be immortalised upon stem cell derivation. The pluripotent state, ‘naïve’ or ‘primed’, depends...
Includes: Supplementary data
Journal Articles
Biol Open (2017) 6 (1): 100–108.
Published: 15 January 2017
... pluripotent stem cells (hiPSCs) demand extensive characterization of isolated clones before their use in downstream applications. By monitoring human fibroblasts undergoing reprogramming for their morphological changes and expression of fibroblast (CD13), pluripotency markers (SSEA-4 and TRA-1-60...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (10): 958–965.
Published: 19 September 2014
... in the realm of Stat3, self-renewal signaling, and pluripotent stem cell biology. Ultimately, this finding may facilitate the development of conditions for the establishment of authentic non-rodent ESCs. ‡ These authors contributed equally to this work § Author for correspondence ( qying...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (7): 614–626.
Published: 20 June 2014
... of loss of pluripotency and Activin/Nodal, BMP4 and Wnt signalling in fate assignment during the early stages of differentiation of mouse ES cells in culture. During the initial period of differentiation, cells exit from pluripotency and enter an Epi-like state. Following this transient stage, and under...
Includes: Supplementary data
Journal Articles
Biol Open (2013) 2 (10): 1049–1056.
Published: 19 August 2013
.... To this end, pluripotent mouse Embryonic Stem (mES) cells have proven to be a useful model system. However, understanding how transcription factors and signalling pathways affect decisions made by individual cells is confounded by the fact that measurements are generally made on groups of cells, whilst...
Includes: Supplementary data
Journal Articles
Biol Open (2013) 2 (6): 613–628.
Published: 10 May 2013
... Afanassieff Summary Not much is known about the molecular and functional features of pluripotent stem cells (PSCs) in rabbits. To address this, we derived and characterized 2 types of rabbit PSCs from the same breed of New Zealand White rabbits: 4 lines of embryonic stem cells (rbESCs), and 3 lines of induced...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (11): 1118–1127.
Published: 07 September 2012
..., senescence, premature aging and associated diseases. Induced pluripotent stem (iPS) cells have been successfully generated from various types of cells and used to model human diseases. It remains unclear whether levels of lamin A influence reprogramming of somatic cells to pluripotent states during iPS...
Includes: Supplementary data