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1-3 of 3
Keywords: Plk1
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Journal Articles
Aisling O'Connor, Stefano Maffini, Michael D. Rainey, Agnieszka Kaczmarczyk, David Gaboriau, Andrea Musacchio, Corrado Santocanale
Journal:
Biology Open
Biol Open (2016) 5 (1): 11–19.
Published: 18 December 2015
... cycle without chromosome segregation occurring. PLK1 kinase plays a major role in mitosis and emerging evidence indicates that PLK1 is also involved in establishing the checkpoint and maintaining SAC signalling. However, mechanistically, the role of PLK1 in the SAC is not fully understood, with several...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2013) 2 (10): 1022–1031.
Published: 6 August 2013
... that, in addition to its role in interstrand crosslinking (ICL) repair, FancJ also regulates the normal centrosome cycle as well as ICL induced centrosome amplification by activating the polo-like kinase 1 (PLK1). We have uncovered a novel function of FancJ in centrosome biogenesis and established centrosome...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2012) 1 (11): 1153–1160.
Published: 14 September 2012
...Toshiyuki Hatano; Greenfield Sluder Summary Mother–daughter centriole disengagement, the necessary first step in centriole duplication, involves Plk1 activity in early mitosis and separase activity after APC/C activity mediates securin degradation. Plk1 activity is thought to be essential...
Includes: Supplementary data
